Pathogens (Basel, Switzerland) · 2021
Genome Analysis of Nicotinamide Adenine Dinucleotide-Independent Mycoplasma synoviae Isolates From Korea.
СтатьяНазвание и аннотация: Перевод в очереди
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Song Yongjun, La Tae-Min, Kim Taesoo, Ahn Gyuhee, Hur Won, Lee Hong-Jae, Shin Hyunjin, Song Seung-Un, Park Eunjin, Lee Joong-Bok, Park Seung-Yong, Choi In-Soo, Lee Sang-Won
Аннотация
Mycoplasma synoviae (MS) is an avian pathogen that causes respiratory disease, infectious synovitis, and eggshell apex abnormalities in chickens. Nicotinamide adenine dinucleotide (NAD)-independent MS was first reported in 1975. Despite the atypical traits of NAD-independent MS, its independence from NAD has not been studied. In this study, we isolated five NAD-independent strains from Korea and assembled their genomes using sequencing reads obtained from Illumina and Oxford Nanopore Technology platforms. The assembled genomes were compared with the genomes of MS-H vaccine strain and type strain WVU1853. We found that the coding sequences of nicotinate phosphoribosyltransferase and glycerol-3-phosphate acyltransferase, and a unique coding sequence were present only in the genomes of NAD-independent isolates.