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Войти в исследования Endocrinologia, diabetes y nutricion · 2017
Recommendations on the effect of antidiabetic drugs in bone.
Consensus StatementСтатьяКлинические рекомендацииНазвание и аннотация: Перевод в очереди
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Rozas-Moreno Pedro, Reyes-García Rebeca, Jódar-Gimeno Esteban, Varsavsky Mariela, Luque-Fernández Inés, Cortés-Berdonces María, Muñoz-Torres Manuel, en representación del Grupo de Trabajo de Osteoporosis y Metabolismo Mineral de la Sociedad Española de Endocrinología y Nutrición
Аннотация
OBJECTIVE: To provide recommendations on the effect of antidiabetic drugs on bone fragility to help select the most adequate antidiabetic treatment, especially in diabetic patients with high risk of fracture.
PARTICIPANTS: Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology.
METHODS: The GRADE system (Grading of Recommendations, Assessment, Development, and Evaluation) was used to establish both the strength of recommendations and the quality of evidence. A systematic search was made in MEDLINE (Pubmed) using the following terms associated to the name of each antidiabetic drug: AND "osteoporosis", "fractures", "bone mineral density", "bone markers", "calciotropic hormones". Papers in English with publication date before 30 April 2016 were reviewed. Recommendations were jointly discussed by the Working Group.
CONCLUSIONS: The document summaries the data on the potential effects of antidiabetic drugs on bone metabolism and fracture risk.
PARTICIPANTS: Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology.
METHODS: The GRADE system (Grading of Recommendations, Assessment, Development, and Evaluation) was used to establish both the strength of recommendations and the quality of evidence. A systematic search was made in MEDLINE (Pubmed) using the following terms associated to the name of each antidiabetic drug: AND "osteoporosis", "fractures", "bone mineral density", "bone markers", "calciotropic hormones". Papers in English with publication date before 30 April 2016 were reviewed. Recommendations were jointly discussed by the Working Group.
CONCLUSIONS: The document summaries the data on the potential effects of antidiabetic drugs on bone metabolism and fracture risk.
Предметные рубрики MeSH
AgedBone RemodelingBone ResorptionContraindications, DrugDiabetes Mellitus, Type 2Dipeptidyl-Peptidase IV InhibitorsFemaleFractures, SpontaneousGlucagon-Like Peptide 1HumansHypoglycemic AgentsInsulinMaleMetforminMiddle AgedOsteoporosisRandomized Controlled Trials as TopicSodium-Glucose Transporter 2 InhibitorsSulfonylurea CompoundsThiazolidinediones