Renal cell carcinoma presenting as nephrotic syndrome complicated by acute renal failure.

A case of minimal change nephropathy occurring in association with a renal cell carcinoma is presented and discussed. The case was unusual in that it was associated with acute renal failure necessitating hemodialysis for five weeks. The renal failure resolved but the nephrotic state persisted in spite of therapy with prednisone then cyclophosphamide. The literature on nephrotic syndrome causing acute renal failure and its association with solid tumors is briefly reviewed.