Public health · 2026
Disparities in testing for latent tuberculosis infection in a large US integrated healthcare system.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ku Jennifer H, Mahale Parag, Qian Lei, Li Zhoxin, Fischer Heidi, Bruxvoort Katia J, Skarbinski Jacek, Lewin Bruno J, Shaw Sally F, Spence Brigitte C, Tartof Sara Y
Аннотация
OBJECTIVES: Disparities in latent tuberculosis infection (LTBI) testing by birth country and socioeconomic status (SES) are not well understood. We used electronic health records from Kaiser Permanente Southern California (2010-2019) to examine disparities in LTBI testing across SES among those born in high-vs. low-tuberculosis (TB) incidence countries.
STUDY DESIGN: Retrospective cohort study.
METHODS: We examined LTBI testing rates and measures of disparities (absolute/relative concentration index, between-group variance, and mean log deviation) across area-level SES and racial/ethnic groups, by birth in a high-vs. low-TB incidence country, with imputed data for missing birth country.
RESULTS: We included 1,740,428 individuals, with a median age of 37.0 years (interquartile range 27.0, 51.0), who were 50.3% female (n = 875,879), and 39.2% Hispanic (n = 682,870); 1,205,853 (69.3%) were born in a country with low TB incidence. Among adults born in low-TB incidence countries (n = 1,205,853; 315.3 tests/10,000 person-years), testing rates remained stable (annual percent change [APC] = -0.69% [95% CI: -1.55, 0.41]). Among adults born in high-TB incidence countries (n = 534,575; 246.7 tests/10,000 person-years), testing rates increased over time (APC = 1.90% [1.14, 2.90]) with a higher rate of increase for those with higher SES. Among individuals born in a high-TB incidence country, disparities by SES and racial/ethnic groups increased over time.
CONCLUSIONS: Disparities in LTBI testing in individuals born in high-vs. low-TB incidence countries decreased overall, but increased disproportionally in those with higher SES among those born in high-TB incidence countries. Continued research is needed to understand the causes of disparities, and to inform interventions to reduce disparities.
STUDY DESIGN: Retrospective cohort study.
METHODS: We examined LTBI testing rates and measures of disparities (absolute/relative concentration index, between-group variance, and mean log deviation) across area-level SES and racial/ethnic groups, by birth in a high-vs. low-TB incidence country, with imputed data for missing birth country.
RESULTS: We included 1,740,428 individuals, with a median age of 37.0 years (interquartile range 27.0, 51.0), who were 50.3% female (n = 875,879), and 39.2% Hispanic (n = 682,870); 1,205,853 (69.3%) were born in a country with low TB incidence. Among adults born in low-TB incidence countries (n = 1,205,853; 315.3 tests/10,000 person-years), testing rates remained stable (annual percent change [APC] = -0.69% [95% CI: -1.55, 0.41]). Among adults born in high-TB incidence countries (n = 534,575; 246.7 tests/10,000 person-years), testing rates increased over time (APC = 1.90% [1.14, 2.90]) with a higher rate of increase for those with higher SES. Among individuals born in a high-TB incidence country, disparities by SES and racial/ethnic groups increased over time.
CONCLUSIONS: Disparities in LTBI testing in individuals born in high-vs. low-TB incidence countries decreased overall, but increased disproportionally in those with higher SES among those born in high-TB incidence countries. Continued research is needed to understand the causes of disparities, and to inform interventions to reduce disparities.