Oral surgery, oral medicine, oral pathology and oral radiology · 2012
Influence of dentures in the initial occurrence site on the prognosis of bisphosphonate-related osteonecrosis of the jaws: a retrospective study.
СтатьяНазвание и аннотация: Перевод в очереди
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Hasegawa Yoko, Kawabe Mutuki, Kimura Hiroto, Kurita Kenichi, Fukuta Jinichi, Urade Masahiro
Аннотация
OBJECTIVE: This retrospective cohort study was conducted to investigate the influence of wearing dentures in the initial occurrence site of bisphosphonate-related osteonecrosis of the jaws (BRONJ).
STUDY DESIGN: A questionnaire regarding the prevalence, therapy, and outcome of jawbone lesions during 2006-08 was mailed to 248 medical institutions with an oral and maxillofacial surgery department in Japan.
RESULTS: Ninety-nine patients wearing dentures had significantly shorter duration until occurrence than 151 patients not wearing dentures. In addition, remission of BRONJ affecting the mandibular canine and premolar region in denture-wearing patients was significantly more difficult. Poor oral hygiene status was found to affect significantly the prognosis of BRONJ in denture-wearing patients. Alcohol habit also delayed remission, but high body mass index promoted remission.
CONCLUSION: Wearing a denture in the initial occurrence site of BRONJ was shown to influence the prognosis of BRONJ, especially in mandibular denture-wearing patients.
STUDY DESIGN: A questionnaire regarding the prevalence, therapy, and outcome of jawbone lesions during 2006-08 was mailed to 248 medical institutions with an oral and maxillofacial surgery department in Japan.
RESULTS: Ninety-nine patients wearing dentures had significantly shorter duration until occurrence than 151 patients not wearing dentures. In addition, remission of BRONJ affecting the mandibular canine and premolar region in denture-wearing patients was significantly more difficult. Poor oral hygiene status was found to affect significantly the prognosis of BRONJ in denture-wearing patients. Alcohol habit also delayed remission, but high body mass index promoted remission.
CONCLUSION: Wearing a denture in the initial occurrence site of BRONJ was shown to influence the prognosis of BRONJ, especially in mandibular denture-wearing patients.
Предметные рубрики MeSH
Administration, IntravenousAdministration, OralAge FactorsAgedAlcohol DrinkingBicuspidBisphosphonate-Associated Osteonecrosis of the JawBody Mass IndexBone Density Conservation AgentsChronic DiseaseCohort StudiesCuspidDenture, CompleteDenture, PartialDenturesDiphosphonatesDrug Therapy, CombinationFemaleFollow-Up StudiesHumansMaleMandibular DiseasesOral HygienePrognosisRetrospective StudiesSmokingTime FactorsTreatment Outcome