Short-Course Tuberculosis Preventive Therapy in a High Migration Setting: Early Experience With 1HP in Cook County, Illinois.

In a U.S. health department TB program serving primarily non-U.S.-born clients, 78% of those evaluated for latent TB infection initiated TB preventive therapy, with 71% completing treatment. Completion was lower among newly arrived migrants. A novel one-month isoniazid-rifapentine regimen (1HP) was well tolerated, with similar completion rates to conventional regimens.