Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology · 2003
[Disc-like changes and type II collagen mRNA expression in the bilaminar zone of rabbit temporomandibular joint following disc displacement].
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Gu Zhi-yuan, Hu Ji-an, Feng Jian-ying, Zhang Zhen-kang, Zhang Yin-kai
Аннотация
OBJECTIVE: To study the adaptive alteration in bilaminar zone of rabbits' temporomandibular joint following disc displacement.
METHODS: Twenty-six Japanese white rabbits were used in this study. Among these rabbits,6 were used as controls. The right discs of other 20 rabbits were displaced anteriorly by operation. Four of these rabbits were killedatn 1, 2, 4, 6 and 8 weeks respectively after surgery. The TMJS were studied by HE staining, Alcin bluen staining and in situ detection of type II collagen mRNA expression.
RESULTS: There appeared cartilage metaplasia after one week following disc displacement. Typical chondrocytes could be found in the bilaminar zone. The new chondrocytes expressed type II collagen.
CONCLUSIONS: The bilaminar zone of TMJ will be remodeled following disc displacement and become a disc-like tissue to function as a disc.
METHODS: Twenty-six Japanese white rabbits were used in this study. Among these rabbits,6 were used as controls. The right discs of other 20 rabbits were displaced anteriorly by operation. Four of these rabbits were killedatn 1, 2, 4, 6 and 8 weeks respectively after surgery. The TMJS were studied by HE staining, Alcin bluen staining and in situ detection of type II collagen mRNA expression.
RESULTS: There appeared cartilage metaplasia after one week following disc displacement. Typical chondrocytes could be found in the bilaminar zone. The new chondrocytes expressed type II collagen.
CONCLUSIONS: The bilaminar zone of TMJ will be remodeled following disc displacement and become a disc-like tissue to function as a disc.