BMC musculoskeletal disorders · 2017
Sex differences in gout characteristics: tailoring care for women and men.
СтатьяНаблюдательное исследованиеПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Harrold Leslie R, Etzel Carol J, Gibofsky Allan, Kremer Joel M, Pillinger Michael H, Saag Kenneth G, Schlesinger Naomi, Terkeltaub Robert, Cox Vanessa, Greenberg Jeffrey D
Аннотация
BACKGROUND: To characterize the differences between women and men with gout.
METHODS: We analyzed a US national cohort of gout patients cared for by rheumatologists.
RESULTS: Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05).
CONCLUSIONS: The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.
METHODS: We analyzed a US national cohort of gout patients cared for by rheumatologists.
RESULTS: Compared with the 1012 men with gout, women with gout (n = 262) were older (71 vs. 61 years, p < 0.001) and had a greater burden of comorbid conditions (p < 0.001 for hypertension, diabetes, renal disease and obesity). Risk factors for gout differed with women more often taking diuretics (p < 0.001), while men more frequently had dietary triggers (p < 0.05).
CONCLUSIONS: The profiles of women and men with gout are markedly different, suggesting a need to tailor treatment recommendations.