Медицинская библиотека · Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology · 2002

Chondrocyte apoptosis in rabbit temporomandibular joint after anterior disc displacement.

Feng Jianying, Gu Zhiyuan, Cao Zhiqiang, Takanori Shibata, Hu Jian, Peng Jiaping

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Аннотация

OBJECTIVE

To study the chondrocyte apoptosis in rabbit temporomandibular joint after anterior disc displacement.

METHODS

Experimental anterior disc displacement was induced surgically in 20 Japanese rabbits without opening their temporomandibular joint bursas. Histopathologic and apoptotic (TUNEL) analysis was used to evaluate the changes in articular cartilage, disc and synovium.

RESULTS

Condyle chondrocyte showed apoptosis most obviously at 1 or 2 weeks after surgery, and apoptotic cells concentrated in proliferative zone and hypertrophic zone. 4 or 6 weeks after surgery, the joint went into a remodelling period.

CONCLUSIONS

Chondrocyte apoptosis in temporomandibular joint will be activated after anterior disc displacement, which initiates the remodelling in temporomandibular joint.

Для цитирования: Feng Jianying, Gu Zhiyuan, Cao Zhiqiang, Takanori Shibata, Hu Jian, Peng Jiaping. Chondrocyte apoptosis in rabbit temporomandibular joint after anterior disc displacement.. Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology. 2002.

Предметные рубрики MeSH

Animals Apoptosis Chondrocytes In Situ Nick-End Labeling Joint Dislocations Rabbits Temporomandibular Joint Temporomandibular Joint Disc

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