Treatment Guidelines and Rehabilitation in Spinal Muscular Atrophy and Duchenne's Muscular Dystrophy.

Duchenne muscular dystrophy (DMD) and spinal muscular atrophy (SMA) are childhood-onset neuromuscular disorders with substantial morbidity and significant rehabilitation needs. Recent advancements, particularly gene-based therapies, have significantly altered the disease trajectory for both conditions, necessitating updated care guidelines. This review will delve into the pathogenesis of DMD and SMA, explore the latest disease-modifying treatments available for each, and comprehensively address the multifaceted rehabilitation needs across the spectrum of disease severity. The aim is to provide a comprehensive overview of current best practices to optimize functional outcomes and quality of life for individuals with DMD and SMA.