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DOI 10.1186/s42358-025-00501-3

Медицинская библиотека · Advances in rheumatology (London, England) · 2025

Reply to the letter on "Brazilian guidelines for the management of tuberculosis infection in immune-mediated inflammatory diseases: is retesting in latent tuberculosis screening appropriate and safe?".

de Souza Viviane Angelina, Caparroz Ana Luiza Mendes Amorim, Trevisani Virginia Fernandes Moça, Tavares Anna Carolina Faria Moreira Gomes, de Melo Ana Karla Guedes, Trajman Anete, de Medeiros-Ribeiro Ana Cristina, de Medeiros Pinheiro Marcelo, Xavier Ricardo Machado, Monticielo Odirlei Andre, de Resende Guimarães Maria Fernanda Brandão, Sztajnbok Flavio, Bombarda Sidney, Chebli Liliana Andrade, Kakehasi Adriana Maria, Bierrenbach Ana Luiza, Reis Ana Paula Monteiro Gomides, Bica Blanca Elena Rios Gomes, Marques Claudia Diniz Lopes, Flores Cristina, Rodrigues Denise Silva, Paiva Eduardo Dos Santos, Matos Eliana Dias, Johansen Fernanda Dockhorn Costa, Bacha Helio Arthur, de Carvalho Joana Starling, Provenza José Roberto, Machado Ketty Lysie Libardi Lira, da Mota Licia Maria Henrique, de Azevedo Valadares Lilian David, da Rocha Loures Marco Antônio Araújo, Dalcolmo Margareth Maria Pretti, de Carvalho Bortoletto Maria Cecilia, Lopes Max Igor Banks Ferreira, de Abreu Vieira Rejane Maria Rodrigues, Romiti Ricardo, Saad-Hossne Rogerio, Ciconelli Rozana Mesquita, Azevedo Valderilio Feijó, Augusto Valéria Maria, Cruz Vitor Alves, Pileggi Gecilmara Cristina Salviato

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Аннотация

In response to a letter addressing the Brazilian guidelines for tuberculosis infection (TBI) screening in immune-mediated inflammatory diseases (IMID), we clarify that the recommendations reflect a structured, evidence-based consensus developed by a multidisciplinary panel, in accordance with internationally accepted standards. We reaffirm the rationale for annual TBI retesting during the first three years of immunosuppressive therapy, particularly with TNF inhibitors, and the outweighed risk of tuberculosis preventive treatment (TPT), given the benefits. These recommendations are aligned with national and international public health policies and underscore the need for flexibility in clinical judgment. Nonetheless, they are conditional, reflecting the limited robustness of the available evidence. Continued dialogue is essential to ensure the safety and protection of IMID patients in high-burden settings like Brazil.

Для цитирования: de Souza Viviane Angelina, Caparroz Ana Luiza Mendes Amorim, Trevisani Virginia Fernandes Moça, Tavares Anna Carolina Faria Moreira Gomes, de Melo Ana Karla Guedes, Trajman Anete, de Medeiros-Ribeiro Ana Cristina, de Medeiros Pinheiro Marcelo, Xavier Ricardo Machado, Monticielo Odirlei Andre, de Resende Guimarães Maria Fernanda Brandão, Sztajnbok Flavio, Bombarda Sidney, Chebli Liliana Andrade, Kakehasi Adriana Maria, Bierrenbach Ana Luiza, Reis Ana Paula Monteiro Gomides, Bica Blanca Elena Rios Gomes, Marques Claudia Diniz Lopes, Flores Cristina, Rodrigues Denise Silva, Paiva Eduardo Dos Santos, Matos Eliana Dias, Johansen Fernanda Dockhorn Costa, Bacha Helio Arthur, de Carvalho Joana Starling, Provenza José Roberto, Machado Ketty Lysie Libardi Lira, da Mota Licia Maria Henrique, de Azevedo Valadares Lilian David, da Rocha Loures Marco Antônio Araújo, Dalcolmo Margareth Maria Pretti, de Carvalho Bortoletto Maria Cecilia, Lopes Max Igor Banks Ferreira, de Abreu Vieira Rejane Maria Rodrigues, Romiti Ricardo, Saad-Hossne Rogerio, Ciconelli Rozana Mesquita, Azevedo Valderilio Feijó, Augusto Valéria Maria, Cruz Vitor Alves, Pileggi Gecilmara Cristina Salviato. Reply to the letter on "Brazilian guidelines for the management of tuberculosis infection in immune-mediated inflammatory diseases: is retesting in latent tuberculosis screening appropriate and safe?".. Advances in rheumatology (London, England). 2025. DOI: 10.1186/s42358-025-00501-3.

Предметные рубрики MeSH

HumansBrazilLatent TuberculosisPractice Guidelines as TopicMass ScreeningImmunosuppressive Agents
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