Proptosis as the manifesting sign of Weber-Christian disease.

PURPOSE: To identify proptosis as a manifesting sign of Weber-Christian disease (recurrent febrile nodular panniculitis).

METHOD: Case report. A 61-year-old man had signs of right proptosis and orbital inflammation that resolved with oral corticosteroid therapy. Orbital inflammation later recurred with associated cutaneous nodules, myalgia, nausea, and malaise.

RESULTS

Rheumatologic evaluation and subcutaneous nodule biopsy led to the diagnosis of Weber-Christian disease. The patient required systemic immunosuppressive agents to control the disease.

CONCLUSION

This case shows the rare finding of proptosis as the manifesting sign of Weber-Christian disease.