Multiple sclerosis and fracture.

Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating central nervous system disease with time and space disseminated lesions that usually occurs in young adults, typically aged between 20 and 45 years. Recently, researches have indicated MS may be associated with increased risk of fracture and osteoporosis. In this review, we aim to identify the fracture risk in MS patients, also address the pathogenic mechanisms and interventions of fracture in those patients.