Journal of cutaneous pathology · 2014
Cutaneous lymphatic malformation characterized by swelling of digits: a report of six cases.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Wang Lei, Gao Tianwen, Wang Gang
Аннотация
BACKGROUND: Cutaneous lymphatic malformations represent a group of heterogeneous diseases. In clinical practice, some cases of cutaneous lymphatic malformation have been found to differ from the well-characterized entities, and are difficult to classify.
OBJECTIVE: To report the clinical, histopathological and immunohistochemical characteristics of six cases of lymphatic malformation characterized by swelling of the digits.
METHODS: Six patients with swelling of the digits were included in this study. Histopathological examination and immunohistochemical staining of CD31, D2-40, Prox1, Wilms tumor 1 (WT-1) and human herpesvirus-8 (HHV-8) were performed for all cases.
RESULTS: All cases were congenital lesions and presented as swelling of single or multiple digits. Histopathologically, the lesions showed proliferation of small-to-medium-sized vessels in the dermis and subcutaneous tissue. These abnormal vessels were positive for CD31, D2-40 and Prox1, and negative for WT-1 and HHV-8.
CONCLUSION: The six cases reported herein represent a specific cutaneous lymphatic malformation different from previously reported entities.
OBJECTIVE: To report the clinical, histopathological and immunohistochemical characteristics of six cases of lymphatic malformation characterized by swelling of the digits.
METHODS: Six patients with swelling of the digits were included in this study. Histopathological examination and immunohistochemical staining of CD31, D2-40, Prox1, Wilms tumor 1 (WT-1) and human herpesvirus-8 (HHV-8) were performed for all cases.
RESULTS: All cases were congenital lesions and presented as swelling of single or multiple digits. Histopathologically, the lesions showed proliferation of small-to-medium-sized vessels in the dermis and subcutaneous tissue. These abnormal vessels were positive for CD31, D2-40 and Prox1, and negative for WT-1 and HHV-8.
CONCLUSION: The six cases reported herein represent a specific cutaneous lymphatic malformation different from previously reported entities.