Nicotine-induced osteonecrosis. A case report.

UNLABELLED: This paper describes a previously unpublished side-effect of nicotine replacement chewing gum and presents useful information about the effects of nicotine on the oral environment. It is important to consider this when diagnosing an area of ulceration.

CLINICAL RELEVANCE: Patients who use nicotine chewing gum should be advised that prolonged contact with the alveolar mucosa should be avoided. They should be told that regular chewing helps dispersal of the nicotine.