Oncogenic osteomalacia due to phosphaturic mesenchymal tumor of the craniofacial sinuses.

BACKGROUND

The phosphaturic mesenchymal tumor of the craniofacial sinuses (mixed connective tissue variant) is an extremely rare, distinctive paraneoplastic syndrome that is frequently associated with oncogenic osteomalacia.

METHODS

In this report is presented a case of 22 years old man indicated four years of progressive generalized pain and weakness, eventually becoming wheel-chair bound. His current presentation was for chest pain resulting from atraumatic rib fractures.

RESULTS

Imaging showed osteoporosis and multiple insufficiency fractures. CT and MRI showed an ethmoid mass. He had no symptoms referable to his nose or sinuses.

CONCLUSIONS

The ethmoid lesion was completely excised, the patient's laboratory parameters returned to normal levels and the patient's symptoms disappeared.