The use of i. v. bisphosphonate in pregnancy-associated osteoporosis--case study.

OBJECTIVE

Diagnosis of pregnancy-associated osteoporosis is often delayed and therapeutic interventions insufficient.

STUDY

DESIGN

A 28-year-old patient (BMI=18.6) with no additional risks for osteoporosis experienced acute lumbosacral pain two months postpartum, while lactating. After conservative therapy, thoracic and lumbar spine were X-rayed: severe pregnancy-associated osteoporosis with vertebral fractures was diagnosed. 2-year treatment with i. v. bisphosphonate ibandronate was initiated (2 mg every 3 months) and calcium and vitamin D supplementation.

RESULTS

Rapid improvement was observed.

Conclusion

In cases with multiple fractures i. v. bisphosphonate leads to substantial decrease of symptoms and further fractures and significant increase of bone mass density (BMD).

CONCLUSION

In severe cases of pregnancy-associated osteoporosis with multiple fractures i. v. biphosphonate therapy leads to a decrease of symptoms and fracture risk and an increase of bone mass density (BMD).