[Symptom with bone metastasis--bone pain, fracture, hypercalcemia].

Bone metastasis is in 60-84% of a metastatic cancer case. Bone metastasis itself does not cause a pain by all means, but even if bone metastasis contributes to 40% of cancer pain, it is said, and it is an important subject of a cancer pain treatment. Because it is a lot progressive as well as an unbearable pain, bone metastasis becomes cause by the fact that the pain is remarkable and inhibits QOL of the patient. On this account that a treatment of bone metastatic pain merely takes a pain by pharmacotherapy. Preventing pathologic fracture and a complication such as spinal cord compression and a treatment of hypercalcemia are important. In addition, we do surgical treatment and radiation therapy for the fracture that occurred positively and must deal generally.