Tissue engineering. Part C, Methods · 2019
A Versatile Protocol for Studying Anterior Cruciate Ligament Reconstruction in a Rabbit Model.
СтатьяНазвание и аннотация: Перевод в очереди
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Hevesi Mario, Crispim João F, Paggi Carlo A, Dudakovic Amel, van Genechten Wouter, Hewett Timothy, Kakar Sanjeev, Krych Aaron J, van Wijnen Andre J, Saris Daniel B F
Аннотация
Anterior cruciate ligament (ACL) injuries are frequent, as >200,000 injuries occur in the United States alone each year. Owing to the risks for associated meniscus and cartilage damage, ACL injuries are a significant source of both orthopedic care and research. Given the extended recovery course after ACL injury, which often lasts 1-2 years, and is associated with limited participation in sports and activities of daily living for patients, there is a critical need for the evolution of new and improved methods for ACL repair. Subsequently, animal models of ACL reconstruction (ACLR) play a key role in the development and initial trialing of novel ACL interventions. This article provides a clear operative description and associated illustrations for a validated, institutional animal care and use committee, and veterinarian approved and facile model of ACLR to serve researchers investigating ACLR.