Dual energy X-ray absorptiometry reference data for Greek population. The impact on diagnosis of using various normal ranges for comparison.

INTRODUCTION

The interpretation of bone mineral density (BMD) measurements and the individual classification of a patient is based on a normal reference range. Unfortunately, not all the manufacturers include in their analysis-software reference values specific for each population.

METHODS AND PATIENTS: In our study, using Lunar's DPX-L densitometer, we measured BMD of the lumbar spine and the femur of 4400 healthy women aged (25-80) years and we calculated the corresponding T- and Z-scores. Multiple regression analysis was applied to examine the dependence of BMD on age and weight. Greek data was compared with American and Italian.

RESULTS

There was a statistically significant difference between Greek and American mean values of all age groups. The Italian normal range is closer to our data and can be reliably used at least as T-scores are concerned. Still, there is a small discrepancy in Z-scores, which might influence patient management.

CONCLUSION

We conclude that Greek reference range should be used for the assessment of osteoporosis of Greek population for better evaluation of bone status and appropriate treatment.