The human factor--the weakest link?

The German Animal-Laboratory-Information-System (ALIS) was used to assist the laboratory animal care program. The transmission of disease from man is a hazard to the health of laboratory animals. Mycoplasmas, Escherichia coli, staphylococci and Listeria were considered as hazards to laboratory animals. Special consideration was given to Escherichia coli strains of O groups 7 and 146 and to different lysotypes of Staphylococcus aureus. Important areas where human mistakes can be prevented are discussed. These include distance of animal quarters from processing areas, the diameter of sanitary sewers, air conditioning, noise, drinking water, cage changing procedures, wetting of animals, quarantine areas and separation of species. Training of laboratory animal technicians in Germany consists of both in-service and formal types. The formal training lasts 2 years. People selected for formal training should be tested to assure they are not allergic to laboratory animal dander.