Диагноз множественных склерозов: 2024 изменения критериев Макдональда.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Montalban Xavier, Lebrun-Frénay Christine, Oh Jiwon, Arrambide Georgina, Moccia Marcello, Amato Maria Pia, Amezcua Lilyana, Banwell Brenda, Bar-Or Amit, Barkhof Frederik, Butzkueven Helmut, Ciccarelli Olga, Chataway Jeremy, Cohen Jeffrey A, Comi Giancarlo, Correale Jorge, Deisenhammer Florian, Filippi Massimo, Fiol Julie, Freedman Mark S, Fujihara Kazuo, Granziera Cristina, Green Ari J, Hartung Hans-Peter, Hellwig Kerstin, Kappos Ludwig, Kimbrough Dorlan, Killestein Joep, Lublin Fred, Marignier Romain, Marrie Ruth Ann, Miller Aaron, Otero-Romero Susana, Ontaneda Daniel, Ramanathan Sudarshini, Reich Daniel, Rocca Maria A, Rovira Àlex, Saidha Shiv, Salter Amber, Sastre-Garriga Jaume, Saylor Deanna, Solomon Andrew J, Sormani Maria Pia, Stankoff Bruno, Tintore Mar, Tremlett Helen, Van der Walt Anneke, Viswanathan Shanthi, Wiendl Heinz, Wildemann Brigitte, Yamout Bassem, Zaratin Paola, Calabresi Peter A, Coetzee Timothy, Thompson Alan J
Аннотация
Оригинал публикации
Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria.
Advances in the understanding of multiple sclerosis and the development of biomarkers of pathophysiology prompted a substantial revision of the 2017 McDonald diagnostic criteria. The new 2024 McDonald criteria provide a unified approach for diagnosing multiple sclerosis in individuals with relapsing or progressive courses throughout the lifespan (ie, from paediatric to late-life presentations). The optic nerve can now serve as a fifth anatomical location within the CNS for diagnosis. The central vein sign, paramagnetic rim lesions, and kappa free-light chain concentrations in CSF can be used, when available, to provide supportive evidence and confer specificity for a diagnosis of multiple sclerosis in specific situations. In certain cases, radiologically isolated syndrome or neurological symptoms that do not constitute a clear attack or progression of disability can fulfil the criteria for a multiple sclerosis diagnosis. We also provide guidance for the diagnosis of multiple sclerosis in older individuals (≥50 years) and those with comorbidities. The 2024 revised criteria should expedite the diagnosis of multiple sclerosis, while maintaining specificity.