Cutaneous Mycobacterioses of Cats and Dogs.

Worldwide, a variety of mycobacterial species have been associated with skin lesions in dogs and cats. Lesions may result from systemic dissemination or local cutaneous inoculation. Only infections with Mycobacterium tuberculosis complex organisms have the potential to be transmitted from companion animals to humans, but even then, zoonotic risk is considered low. Diagnosis of mycobacterial infections is based on identification of intralesional acid-fast bacteria using cytology or histopathology, culture at experienced facilities, and use of PCR-sequencing. Treatment typically requires prolonged combination therapy with antimycobacterial drugs, and the prognosis varies depending on the mycobacterial species involved and presence of underlying immunosuppression.