Medicine · 2024
A rare case report of concurrent cryptococcal, streptococcal, and tuberculous meningitis in a patient with pulmonary tuberculosis.
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Bi Dewu, Luo Xiaolu, Tang Xike, Luo Xiaocheng, Mo Lida
Аннотация
RATIONALE: Meningitis caused by concurrent infections with Cryptococcus neoformans, Streptococcus equi subsp. equi, and Mycobacterium tuberculosis is extremely rare.
PATIENT CONCERNS: We present the case of a 63-year-old male patient who presented with headaches, dizziness, nausea, vomiting, and fever for the past 3 weeks.
DIAGNOSES: The patient was diagnosed with concurrent cryptococcal, streptococcal, and tuberculous meningitis.
INTERVENTIONS: The patient received isoniazid, rifampicin, ethambutol, and levofloxacin for 1 month, in addition to liposomal amphotericin B with flucytosine for 2 weeks, followed by fluconazole with flucytosine for additional 2 weeks.
OUTCOMES: The symptoms improved, and outpatient therapy was continued.
LESSONS: Infectious meningitis requires a combination of microscopy, culture, and rapid molecular diagnostics for early diagnosis and treatment.
PATIENT CONCERNS: We present the case of a 63-year-old male patient who presented with headaches, dizziness, nausea, vomiting, and fever for the past 3 weeks.
DIAGNOSES: The patient was diagnosed with concurrent cryptococcal, streptococcal, and tuberculous meningitis.
INTERVENTIONS: The patient received isoniazid, rifampicin, ethambutol, and levofloxacin for 1 month, in addition to liposomal amphotericin B with flucytosine for 2 weeks, followed by fluconazole with flucytosine for additional 2 weeks.
OUTCOMES: The symptoms improved, and outpatient therapy was continued.
LESSONS: Infectious meningitis requires a combination of microscopy, culture, and rapid molecular diagnostics for early diagnosis and treatment.