Asia-Pacific consensus for the management of osteoporosis in men.
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Huang Chun-Feng, Ho Cheng-Jung, Lin Sung-Yen, Hwang Jawl-Shan, Tai Ta-Wei, Chen Jung-Fu, Tu Shih-Te, Chan Ding-Cheng, Yang Rong-Sen, Chen Hsuan-Yu, Tsai Keh-Sung, Cheng Tien-Tsai, Chen Fang-Ping, Hung Wei-Chieh, Chang Yin-Fan, Han Der-Sheng, Chandran Manju, Bin Ang Seng, Lee Joon Kiong, Yeap Swan Sim, Chung Yoon-Sok, Kim Kwang-Kyoun, Ebeling Peter, Jaisamrarn Unnop, Pandey Dipendra, Ferrari Serge, McCloskey Eugene, Charatcharoenwitthaya Natthinee, Taguchi Akira, Lekamwasam Sarath, Van Nguyen Tuan, Lewiecki E Michael, Saag Kenneth G, Tsai Ching-Chou, Marín Fernando, Mori Satoshi, Hwang Kyu Ri, Li-Yu Julie, Carey John J, Kendler David, Cheung Ching Lung, Huang Huei-Kai, Kuptniratsaikul Vilai, Chan Wing P, Chan Siew Pheng, Ho-Pham Lan T, Hew Fen Lee, Shi Huipeng, Reid Ian, Kanis John A, Chen Chung-Hwan, Wu Chih-Hsing
Аннотация
PURPOSE: To establish evidence-based, region-specific guidelines for the management of male osteoporosis in the Asia-Pacific region, addressing demographic and lifestyle factors.
METHODS: Expert feedback was gathered through premeeting reviews, consensus conferences, and collaborative discussions. A life-course approach was employed to align international best practices with Asia-Pacific-specific needs, emphasizing continuous monitoring and intervention from middle age onward.
RESULTS: The 12 consensus strategies systematically approach male osteoporosis management, addressing screening, diagnosis, treatment, and long-term follow-up. Recommendations include the assessment of fracture risk for men aged 50 years and above, use of dual-energy X-ray absorptiometry (DXA) testing for men aged 70 years and above, lifestyle modifications, and pharmacological interventions such as bisphosphonates, denosumab, and anabolic agents for high-risk patients. Secondary causes of osteoporosis were highlighted, along with the establishment of fracture liaison services (FLSs) to improve long-term care. A life-course approach was proposed to optimize bone health throughout men's lives.
CONCLUSION: This consensus provides a comprehensive framework tailored to the Asia-Pacific region for diagnosing, preventing, and managing osteoporosis in men. By addressing region-specific challenges and promoting evidence-based interventions, the latest guidelines incorporating the consensus may depict the conceptual direction in reducing fracture risk and improving long-term bone health outcomes for osteoporosis in men.