La Revue de medecine interne · 2014
[Systemic sclerosis and occupational exposures: About a case in a driller-powderman].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Boulanger M, Bienvenu B, Marquignon M-F, Letourneux M, Clin B
Аннотация
INTRODUCTION: Erasmus' syndrome is the association between systemic sclerosis and silica exposure.
CASE REPORT: We report a case of this syndrome in a driller-powderman exposed to silica and nitro compounds contained in explosives.
CONCLUSION: Physiopathology and etiologies of systemic sclerosis are still not well known. However, nitric oxide, a product of nitro compounds metabolism, is involved in the physiopathology of the disease: it seems thus licit to wonder about the consequences of an uncontrolled occupational exposure to nitric oxide on the vascular function, already damaged by systemic sclerosis. To a wider extent, our report highlights the importance of a comprehensive and detailed collection of occupational exposures for patients diagnosed with systemic sclerosis.
CASE REPORT: We report a case of this syndrome in a driller-powderman exposed to silica and nitro compounds contained in explosives.
CONCLUSION: Physiopathology and etiologies of systemic sclerosis are still not well known. However, nitric oxide, a product of nitro compounds metabolism, is involved in the physiopathology of the disease: it seems thus licit to wonder about the consequences of an uncontrolled occupational exposure to nitric oxide on the vascular function, already damaged by systemic sclerosis. To a wider extent, our report highlights the importance of a comprehensive and detailed collection of occupational exposures for patients diagnosed with systemic sclerosis.