Steroid-induced scleroderma renal crisis in an at-risk patient.

Scleroderma renal crisis (SRC) is a major complication of systemic sclerosis (SSc). We present a case of a patient who died of complications attributable to SRC in the context of recently diagnosed SSc. We review the typical clinical and laboratory features of SSc present in our patient and highlight those that identify greater risk of progression to SRC. Particular risk factors for SRC include cutaneous involvement, positive anti-RNA polymerase III antibodies and use of corticosteroids (CS). The authors emphasise the importance of risk evaluation when choosing to use CS in patients with SSc.