Singapore Advanced Cardiac Life Support Guidelines 2026.

Advanced cardiovascular life support (ACLS) provides a structured approach to the management of cardiac arrest and life-threatening arrhythmias, building on early recognition, high-quality cardiopulmonary resuscitation (CPR), and timely defibrillation. The 2026 Singapore ACLS guidelines present updated, evidence-based recommendations informed by the latest guidance from the American Heart Association and the European Resuscitation Council. Key updates include optimisation of CPR quality, integration of point-of-care ultrasonography, and refined use of pharmacological and electrical therapies during resuscitation. The role of extracorporeal CPR as a rescue strategy in selected patients and the importance of organised post-resuscitation care in improving neurological outcomes are emphasised. Management of tachyarrhythmias and bradyarrhythmias is also addressed. Special circumstances, including pulmonary embolism, drowning and cardiac arrest during pregnancy, are discussed. These guidelines aim to standardise practice and improve survival and functional outcomes following cardiac arrest in Singapore.