Medecine et maladies infectieuses · 2017
Pristinamycin-induced arthralgia and myalgia: Analysis of the French Pharmacovigilance Database.
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Denis Prevot M, Thillard E M, Walther J, Veyrac G, Laroche M L, Gautier S, Auffret M
Аннотация
INTRODUCTION: Pristinamycin is an antibiotic of the streptogramin family; few adverse effects of this drug are reported, only cutaneous and digestive ones. Arthralgia and myalgia may however be observed although not mentioned in the summary of product characteristics.
OBJECTIVE: Description and analysis of cases of pristinamycin-induced arthralgia and/or myalgia registered in the French database of pharmacovigilance.
METHOD: We carried out a targeted search of the database, selecting case patients presenting with arthralgia and muscle pain and excluding those associated with sensitivities or allergies to pristinamycin.
RESULTS: We retrieved 15 case patients of pristinamycin-induced arthralgia and myalgia. Pristinamycin was the only potentially incriminated drug for seven case patients.
CONCLUSION: Although not serious, this adverse effect deserves to be better known by physicians to optimize therapeutic management.
OBJECTIVE: Description and analysis of cases of pristinamycin-induced arthralgia and/or myalgia registered in the French database of pharmacovigilance.
METHOD: We carried out a targeted search of the database, selecting case patients presenting with arthralgia and muscle pain and excluding those associated with sensitivities or allergies to pristinamycin.
RESULTS: We retrieved 15 case patients of pristinamycin-induced arthralgia and myalgia. Pristinamycin was the only potentially incriminated drug for seven case patients.
CONCLUSION: Although not serious, this adverse effect deserves to be better known by physicians to optimize therapeutic management.