Toxic Epidermal Necrolysis and Sepsis.

UNLABELLED: A 63-year-old male patient suffered from myalgia, arthralgia cough and erythematous macules, with confluence to the thorax, limbs, thighs and the scrotum. The erythematous macules evolved to blisters with a positive Nikolsky's sign. A cutaneous biopsy revealed satellite cell necrosis. Administration of immunoglobulins resulted in a favourable evolution of the cutaneous lesions. Toxic epidermal necrolysis (TEN) is a rare and potentially fatal mucocutaneous disease. Early recognition, diagnosis and therapy are of the utmost importance.

LEARNING POINTS: Toxic epidermal necrolysis (TEN) is a rare and potentially fatal mucocutaneous disease.TEN requires early diagnosis, appropriate workup and treatment to minimise potential morbidity and mortality.Today immunoglobulin therapy is the most accepted form of treatment for TEN.