Brucellosis in the United States: role and significance of wildlife reservoirs.

Regulatory programs for brucellosis in domestic livestock have been active in the U.S. for almost 80 years. Wildlife reservoirs of brucellosis include bison (Bison bison) and elk (Cervus elaphus nelsonii) for Brucella abortus whereas Brucella suis is the predominant species infecting feral swine. The persistence of brucellosis in wildlife reservoirs poses a risk for reintroduction of Brucella into domestic livestock. Reducing the prevalence of brucellosis in wildlife reservoirs is anticipated to be complicated and costly, and the problem is unlikely to be quickly resolved. Although some tools are currently available for use in the wildlife reservoirs, development of new vaccines, diagnostics, and management procedures will most likely be needed for effective control of brucellosis.