Archivos de cardiologia de Mexico · 2026
Pulmonary embolism consensus.
СтатьяConsensus StatementНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Quintana Miguel A, Perea Joaquín, López-Ruiz Arnaldo, Soto Mauricio, Castro Marildes, Silva-Cortés Rafael, Arias Alexandra, Rivera Alex, Álvarez Manuel, Sanhueza Patricio, Quispe Yaqueline, Tenezaca Roger, Costabel Juan P, Saavedra Iván, Colque Roberto, Diez-Pérez Ismenia, Pérez Gonzalo, Morejón Paola, Gan-Fernández Karina, Mogollón Adriana, Cardona Marcelo, Ibarrola Dahiana, Villarreal Ricardo
Аннотация
BACKGROUND: Pulmonary embolism (PE) remains a major cause of cardiovascular morbidity and mortality. Despite significant advances in diagnosis and treatment, important challenges persist in the early identification of patients at risk of clinical deterioration and in the integration of clinical, imaging, and biomarker data for more accurate risk stratification.
METHOD: A multidisciplinary panel of experts reviewed the available scientific evidence, including international guidelines, randomized clinical trials, observational studies, and contemporary registries. Recommendations were developed through a structured consensus process, with particular emphasis on areas of uncertainty or ongoing evolution in clinical practice.
RESULTS: This document updates recommendations on the diagnosis, risk stratification, anticoagulation, reperfusion therapies, and follow-up of patients with acute PE. A key focus is the concept of dynamic risk assessment, recognizing that clinical status may change significantly during the first hours and days after diagnosis. As an innovative proposal, the Integrated Cardiorespiratory Involvement System (SIAC) is introduced as a complementary framework that integrates hemodynamic parameters, right ventricular dysfunction, gas exchange impairment, biomarker profile, and clinical evolution. SIAC is designed to enhance traditional risk stratification models by enabling serial bedside reassessment and facilitating early identification of patients at risk of clinical deterioration and adverse outcomes.
CONCLUSIONS: Modern management of acute PE requires a comprehensive and dynamic approach. This consensus integrates current evidence and proposes SIAC as a complementary tool to improve prognostic assessment and support more individualized therapeutic decision-making.
METHOD: A multidisciplinary panel of experts reviewed the available scientific evidence, including international guidelines, randomized clinical trials, observational studies, and contemporary registries. Recommendations were developed through a structured consensus process, with particular emphasis on areas of uncertainty or ongoing evolution in clinical practice.
RESULTS: This document updates recommendations on the diagnosis, risk stratification, anticoagulation, reperfusion therapies, and follow-up of patients with acute PE. A key focus is the concept of dynamic risk assessment, recognizing that clinical status may change significantly during the first hours and days after diagnosis. As an innovative proposal, the Integrated Cardiorespiratory Involvement System (SIAC) is introduced as a complementary framework that integrates hemodynamic parameters, right ventricular dysfunction, gas exchange impairment, biomarker profile, and clinical evolution. SIAC is designed to enhance traditional risk stratification models by enabling serial bedside reassessment and facilitating early identification of patients at risk of clinical deterioration and adverse outcomes.
CONCLUSIONS: Modern management of acute PE requires a comprehensive and dynamic approach. This consensus integrates current evidence and proposes SIAC as a complementary tool to improve prognostic assessment and support more individualized therapeutic decision-making.