Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit · 2011
Patients' report of statins use and side-effects in a sample of hospitalized cardiac patients in the Islamic Republic of Iran.
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Mashayekhi S O, Ghandforoush-Sattari M, Baghdadchi M E, Kheyri M
Аннотация
We aim to study the prevalence of the side-effects of statins among Iranians patients admitted to a cardiac-specialized hospital and had taken statins prior to hospitalization. Data was collected between September 2007 and March 2008 and 200 patients were enrolled. A questionnaire was completed using the patients' records and by interviewing the patients. The mean age of the participants was 61.5 (SD 12.3) years and 63% were males. The most commonly used statins was atrovastatin (99% of the patients). In all, 63.5% of the participants reported experiencing side-effects due to statins. The reported side-effects were respiratory (18.5%), headache (16.5%), rash (0.5%) and allergic reactions (5%); 9.5% reported (4%) and gastrointestinal effect muscle-related side-effects such as myalgia. Although, the clinical benefits outweigh the small risk of liver failure and myopathy, clinicians should be aware of the side-effects of statins.