Vanishing bone disease.

A young lady presented with progressive hypertrophy and lateral curvature of the left leg of long duration. The overlying skin showed remarkable vascular prominence. The limb involvement was asymptomatic except minor restriction of movements. Radiologically, there was diffuse osteolysis of the tibia and fibula suggestive of vanishing bone disease. This rare condition bears a clinical resemblance to other disorders with vascular malformations and limb hypertrophy. The differential diagnosis of vanishing bone disease, from the dermatologists' point of view has been discussed.