m+Medelevator.RU
← Поиск публикаций
Cureus · 2026

Purpura Fulminans in a 22-Month-Old Child: Early Recognition and Favorable Outcome Without Limb Loss.

Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…

История · было → стало

Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.

Hamidoglu Hoor, Abu Tawileh Roa'a, Wasim Sana, Alshaibah Raihanah, Musabeh Mohamed Alshehhi Mariam

Аннотация

Purpura fulminans (PF) is a rare but life-threatening complication of meningococcal sepsis marked by rapidly progressive hemorrhagic skin lesions, disseminated intravascular coagulation, and microvascular thrombosis, often leading to high mortality and limb loss. We report a previously healthy 22-month-old boy who presented with fever, followed by rapidly evolving ecchymotic lesions and laboratory evidence of septic shock with disseminated intravascular coagulopathy (DIC) and markedly reduced protein C levels; blood culture and cerebrospinal fluid (CSF) polymerase chain reaction (PCR) confirmed Neisseria meningitidis. He was managed promptly with intravenous antibiotics, fluid resuscitation, vasopressors, and blood products. Therapeutic heparin was initiated as an individualized adjunct during the compensated phase of shock, although its benefit in this context remains uncertain. Early recognition and multidisciplinary intervention were associated with rapid stabilization and complete recovery without necrosis, limb loss, neurological deficits, or growth abnormalities. This case underscores the critical importance of early dermatologic recognition and aggressive management to prevent irreversible complications.

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты