Pathologica · 2004
Osteosarcoma with rhabdomyosarcomatous component or so-called malignant mesenchymoma of bone.
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Mrad K, Sassi S, Smida M, Oubiche F, Mekni A, Romdhane K Ben
Аннотация
BACKGROUND: Primary malignant mesenchymoma of the bone is a rare neoplasm consisting of two or more unrelated malignant mesenchymal components. The literature reports fewer than 20 cases, most of which were composed of osteosarcoma and liposarcoma.
OBSERVATION: We report an exceedingly rare case of primary malignant mesenchymoma of bone composed of rhabdomyosarcoma, osteosarcoma, and a minor chondrosarcoma component, arising in the right proximal humerus of a 15-year-old girl. The rhabdomyosarcomatous component was present in the initial biopsy and persisted in surgical specimen following chemotherapy.
CONCLUSION: Effect of chemotherapy is enigmatic since rhabdomyosarcomatous component could appear, persist or disappear after chemotherapy according to literature.
OBSERVATION: We report an exceedingly rare case of primary malignant mesenchymoma of bone composed of rhabdomyosarcoma, osteosarcoma, and a minor chondrosarcoma component, arising in the right proximal humerus of a 15-year-old girl. The rhabdomyosarcomatous component was present in the initial biopsy and persisted in surgical specimen following chemotherapy.
CONCLUSION: Effect of chemotherapy is enigmatic since rhabdomyosarcomatous component could appear, persist or disappear after chemotherapy according to literature.
Предметные рубрики MeSH
AdolescentAntimetabolites, AntineoplasticBone NeoplasmsChondrosarcomaCombined Modality TherapyDesminDiagnosis, DifferentialFatal OutcomeFemaleFibrosarcomaHumansHumerusMesenchymomaMethotrexateNeoplasm ProteinsNeoplasms, Multiple PrimaryOsteolysisOsteosarcomaPostoperative ComplicationsPulmonary EmbolismRadiographyRhabdomyosarcomaSarcoma, Ewing