European journal of dentistry · 2020
Metastatic Biphasic Primitive Tumor in the Mandible of a Child.
СтатьяНазвание и аннотация: Перевод в очереди
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Pinheiro Tiago Novaes, Leite Milena Gomes Melo, Bindá Fábio Arruda, Dutra André Luiz Tannus, Sarmento Naelka, Cabral Lioney Nobre, Consolaro Alberto, Bacchi Carlos Eduardo
Аннотация
Pediatric mandibular tumors present an aggressive biological behavior and difficult diagnosis. A wide range of odontogenic and nonodontogenic tumors comprise the spectrum of these lesions. We report a case of a 1-year-old male child patient showing facial asymmetry symptomatic of an expansive lesion extending throughout the body and ramus of the left hemimandible with a diameter of 8 cm. The histopathological report suggested a high-grade mucoepidermoid carcinoma (MEC), recommending further immunohistochemical investigation of the ectomesenchymal or neuroectodermal origin of the tumor cells. The patient evolved with extensive bilateral pleural effusion followed by metastasis in the middle third of the right humerus, and died 2 months after the first biopsy procedure by acute renal failure with tubular necrosis, before a final inconclusive immunohistochemical report was reached. The lack of resources for less-favored regions of Brazil impairs rapid biomolecular examinations such as immunohistochemical resulting in delay of appropriate therapeutic procedures.