[Evidence-based clinical guidelines of acute atlas fractures in adults (2025 edition)].

In 2015, the Spinal Trauma Working Group of the Chinese Association of Orthopaedic Surgeons (CAOS) developed the Evidence-Based Clinical Guidelines of Acute Atlantoaxial Fractures in Adults based on literature published prior to 2014. Over the past decade, extensive research of acute atlantoaxial fractures in adults has been conducted globally, with the number of published studies in Chinese and English exceeding the cumulative total of all previous literature. To address evolving clinical needs and align with evidence-based principles, CAOS initiated a comprehensive revision of the guidelines. Following the methodology framework of the 2015 edition, the expert panel systematically retrieved, screened, and synthesized literature published between January 1, 2015, and December 31, 2023, integrating evidence from the original guideline. The expert panel carefully analyzed the medical evidence provided by the literature and rigorously graded it according to evidence-based medicine standards. The 2025 guidelines retain prior recommendations while introducing updates and integrating new evidence, ultimately proposing 6 clinical questions paired with 6 evidence-based recommendations. Each recommendation is accompanied by detailed interpretations and supporting rationale to enhance clinical understanding and application.