Pregnancy outcomes in patients with tubal infertility following laparoscopic treatment: a multivariate predictive study.

BACKGROUND

Tubal infertility represents a large portion of female infertility. This study analyzed the pregnancy outcomes of patients with tubal infertility after laparoscopic treatment. A multivariate predictive analysis was also conducted.

METHODS

The clinical data of 92 patients admitted in our hospital from March 2015 to March 2018 with tubal infertility were analyzed. According to the inclusion and exclusion criteria, 87 patients were finally included, and all patients were treated with laparoscopy. The clinical data of all study subjects were collected, including age, years of infertility, type of infertility, history of pelvic surgery, history of tubal pregnancy, history of artificial abortion, and lowest tubal function score. The patients were followed up for two years, and multiple logistic regression was used to analyze the factors affecting the pregnancy outcomes of patients with tubal infertility after laparoscopic treatment. The receiver operating characteristic (ROC) curve was used to analyze the predictive values.

RESULTS

Among the 87 patients, 63 cases (72.41%) had successful pregnancies at follow-up, and 24 cases (27.58%) were not pregnant. The time of follow up (half a year, 1 year, and 2 years) was not significantly different between the pregnant and the non-pregnant groups. There were no significant differences in the infertility types, pelvic surgery history, and induced abortion history between two groups (P>0.05), However, there were differences in the age, years of infertility, tubal pregnancy history, and lowest tubal function score (P<0.05). Multivariate analyses showed that the patient's age over 35 years, a lowest tubal function score indicating severe injury, and a history of tubal pregnancy were independent risk factors for the pregnancy outcome of patients with tubal infertility after laparoscopic treatment (P<0.05). The area under the ROC curve for age, lowest tubal function score, tubal pregnancy history, and the three combined curves were 0.792, 0.852, 0.816, and 0.949, respectively.

CONCLUSIONS

The age of the patient, the lowest tubal function score, and the tubal pregnancy history are independent risk factors for the pregnancy outcome of patients with tubal infertility after laparoscopic treatment. Furthermore, the combination of the three risk factors can be used as a predictor of the pregnancy outcome in patients with tubal infertility after laparoscopic treatment.