Deutsche medizinische Wochenschrift (1946) · 2005
[Reversible autonomic dysfunction in a young woman with septic multiple organ dysfunction syndrome].
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Schmidt H, Flieger R R, Hennen R, Tymiec P, Winkler M, Hoyer D, Buerke M, Müller-Werdan U, Werdan K
Аннотация
HISTORY: A 24-year-old woman was admitted for treatment of a meningococcal infection accompanied by fulminant autonomic dysfunction.
INVESTIGATIONS: Laboratory tests indicated acute renal failure and disseminated intravascular coagulopathy (creatinine 183 mmol, D-dimer 1.52 mg/l). The initial central venous oxygen saturation was 60-65%. The diagnosis of severe septic shock was supported by a high procalcitonin level of 66.7 ng/ml, CRP of 79.8 mg/l, and a WBC count of 12.2 Gpt/l.
TREATMENT AND COURSE: Treatment of sepsis with antibiotics (ciprofloxacin, penicillin G, ceftriaxon and erythromycin in standard dosages), activated protein-C, hydrocortisone and GMA-embedded immunoglobulin led to complete cure and restoration of normal autonomic function.
CONCLUSIONS: This case shows that even in multiple organ dysfunction syndrome autonomic dysfunction can occur which is improved by adequate treatment.
INVESTIGATIONS: Laboratory tests indicated acute renal failure and disseminated intravascular coagulopathy (creatinine 183 mmol, D-dimer 1.52 mg/l). The initial central venous oxygen saturation was 60-65%. The diagnosis of severe septic shock was supported by a high procalcitonin level of 66.7 ng/ml, CRP of 79.8 mg/l, and a WBC count of 12.2 Gpt/l.
TREATMENT AND COURSE: Treatment of sepsis with antibiotics (ciprofloxacin, penicillin G, ceftriaxon and erythromycin in standard dosages), activated protein-C, hydrocortisone and GMA-embedded immunoglobulin led to complete cure and restoration of normal autonomic function.
CONCLUSIONS: This case shows that even in multiple organ dysfunction syndrome autonomic dysfunction can occur which is improved by adequate treatment.
Предметные рубрики MeSH
AdultAnti-Bacterial AgentsArrhythmias, CardiacAutonomic Nervous System DiseasesChemoreceptor CellsCombined Modality TherapyCritical CareDrug Therapy, CombinationElectrocardiographyFemaleHeart RateHumansImmunoglobulin AImmunoglobulin MMeningococcal InfectionsMultiple Organ FailureProtein CRecombinant ProteinsSensory ThresholdsShock, Septic