[Obstetrical and gynecological relevance of inflammatory bowel disease].

INTRODUCTION

Inflammatory bowel disease may show a life long persistence, while female fertility is time-limited.

AIM: The aim of the authors was to obtain more knowledge about the obstetrical-gynecological aspects of this disorder.

METHODS

The authors evaluated 100 patients with inflammatory bowel disease and 100 healthy women with a self-composed questionnaire.

RESULTS

Menarche occurred significantly earlier in patients than in controls (p = 0,03). Either the activity of the disease, or the therapy itself may initiate irregularities in the menstrual cycle. Patients used contraceptives less frequently than controls (p = 0,002), and the time from family-planning to conception was longer in patients. Symptoms of bowel disease during pregnancy were not as severe as before and after pregnancy (p<0,001). Excess weight had a beneficial effect on symptoms during pregnancy (p = 0,042) and on the frequency of complications. Preterm birth and low birth weight were more frequent in newborns of patients (p = 0,019).

CONCLUSION

Pregnancy has positive effect on the symptoms of inflammatory bowel disease in case gestation occurs in a stable period of the inflammatory bowel disease.