MMWR. Morbidity and mortality weekly report · 2017
Rapid Laboratory Identification of Neisseria meningitidis Serogroup C as the Cause of an Outbreak - Liberia, 2017.
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Patel Jaymin C, George Josiah, Vuong Jeni, Potts Caelin C, Bozio Catherine, Clark Thomas A, Thomas Jerry, Schier Joshua, Chang Arthur, Waller Jessica L, Diaz Maureen H, Whaley Melissa, Jenkins Laurel T, Fuller Serena, Williams Desmond E, Redd John T, Arthur Ray R, Taweh Fahn, Vera Walker Yatta, Hardy Patrick, Freeman Maxwell, Katawera Victoria, Gwesa Gulu, Gbanya Miatta Z, Clement Peter, Kohar Henry, Stone Mardia, Fallah Mosoka, Nyenswah Tolbert, Winchell Jonas M, Wang Xin, McNamara Lucy A, Dokubo E Kainne, Fox LeAnne M
Аннотация
On April 25, 2017, a cluster of unexplained illness and deaths among persons who had attended a funeral during April 21-22 was reported in Sinoe County, Liberia (1). Using a broad initial case definition, 31 cases were identified, including 13 (42%) deaths. Twenty-seven cases were from Sinoe County (1), and two cases each were from Grand Bassa and Monsterrado counties, respectively. On May 5, 2017, initial multipathogen testing of specimens from four fatal cases using the Taqman Array Card (TAC) assay identified Neisseria meningitidis in all specimens. Subsequent testing using direct real-time polymerase chain reaction (PCR) confirmed N. meningitidis in 14 (58%) of 24 patients with available specimens and identified N. meningitidis serogroup C (NmC) in 13 (54%) patients. N. meningitidis was detected in specimens from 11 of the 13 patients who died; no specimens were available from the other two fatal cases. On May 16, 2017, the National Public Health Institute of Liberia and the Ministry of Health of Liberia issued a press release confirming serogroup C meningococcal disease as the cause of this outbreak in Liberia.