MedElevator
Войти в исследования JPGN reports · 2026
Pediatric vascular compression of the esophagus: Endoluminal functional lumen imaging probe as a complement to imaging and endoscopy.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Hoskins Brett J, Bose Paroma, Pitman Ryan T
Аннотация
OBJECTIVES: Vascular anomalies can cause extrinsic esophageal compression, leading to dysphagia or feeding difficulties in children. Diagnosis typically relies on imaging and endoscopy, which may under- or overestimate functional narrowing. Endoluminal functional lumen imaging probe (EndoFLIP) provides luminal parameters in real-time, but its role in vascular compression is not well-defined.
METHODS: We retrospectively reviewed children with vascular anomalies who underwent upper endoscopy with EndoFLIP (July 2021-April 2025). Demographics, imaging, endoscopic/EndoFLIP findings, and outcomes were recorded. In select cases, paired measurements at the lower esophageal sphincter (LES) and compression site were compared at matched balloon volumes.
RESULTS: Eight patients (mean age 12.1 years; range 6-17; 5 females) were included. Vascular anomalies included left aortic arch with aberrant right subclavian artery (n = 5), double aortic arch (n = 2), and right aortic arch with anomalous left subclavian artery (n = 1). EndoFLIP detected narrowing in 6/8 (75%), compared with 4/8 (50%) on endoscopy and 6/7 (86%) on upper gastrointestinal (UGI) series. Two patients had narrowing on EndoFLIP despite normal endoscopy; two others had UGI narrowing but normal EndoFLIP and endoscopy. Paired measurements (n = 2) showed markedly reduced diameter and distensibility at the compression site versus the LES. Management included surgical repair (n = 3), dietary modification (n = 2), and proton-pump inhibitor therapy (n = 3), with variable symptom improvement. No procedural complications occurred.
CONCLUSIONS: EndoFLIP was safe, feasible, and provided meaningful complementary physiologic information in this heterogeneous cohort. These preliminary findings support a potential diagnostic role for EndoFLIP in esophageal vascular compression, warranting confirmation in larger, standardized, prospective studies.
METHODS: We retrospectively reviewed children with vascular anomalies who underwent upper endoscopy with EndoFLIP (July 2021-April 2025). Demographics, imaging, endoscopic/EndoFLIP findings, and outcomes were recorded. In select cases, paired measurements at the lower esophageal sphincter (LES) and compression site were compared at matched balloon volumes.
RESULTS: Eight patients (mean age 12.1 years; range 6-17; 5 females) were included. Vascular anomalies included left aortic arch with aberrant right subclavian artery (n = 5), double aortic arch (n = 2), and right aortic arch with anomalous left subclavian artery (n = 1). EndoFLIP detected narrowing in 6/8 (75%), compared with 4/8 (50%) on endoscopy and 6/7 (86%) on upper gastrointestinal (UGI) series. Two patients had narrowing on EndoFLIP despite normal endoscopy; two others had UGI narrowing but normal EndoFLIP and endoscopy. Paired measurements (n = 2) showed markedly reduced diameter and distensibility at the compression site versus the LES. Management included surgical repair (n = 3), dietary modification (n = 2), and proton-pump inhibitor therapy (n = 3), with variable symptom improvement. No procedural complications occurred.
CONCLUSIONS: EndoFLIP was safe, feasible, and provided meaningful complementary physiologic information in this heterogeneous cohort. These preliminary findings support a potential diagnostic role for EndoFLIP in esophageal vascular compression, warranting confirmation in larger, standardized, prospective studies.