A Rare Case of Uterine Embryonal Rhabdomyosarcoma in a Postmenopausal Woman.

This report describes a rare presentation of embryonal rhabdomyosarcoma (ERMS) in a 76-year-old postmenopausal woman who presented with several months of unreported vaginal bleeding followed by obstructive urinary symptoms. Imaging revealed a large uterine mass, and biopsy with immunohistochemical staining confirmed ERMS characterized by high-grade histopathologic features. Given her advanced age, comorbidities, poor functional status, and extensive tumor burden, the patient opted for palliative care focused on comfort and quality of life. This case highlights the diagnostic challenges, aggressive nature, and poor prognosis associated with adult ERMS. It reinforces the importance of promptly evaluating postmenopausal bleeding and raising clinician awareness to facilitate earlier diagnosis and improve outcomes in elderly patients.