The Roles of Systemic Lupus Erythematosus and Immunoglobulin A Nephropathy in Glomerular Disease.

Two autoimmune diseases that can negatively affect kidney function are systemic lupus erythematosus (SLE) and immunoglobulin A (IgA) nephropathy. Autoimmune diseases occur when autoantibodies attack intrinsic tissue and generate inflammation in multiple body tissues, sometimes targeting specific organs. There is no cure for either SLE or IgA nephropathy, but both disorders may be medically managed.