Diffuse vaginal adenosis. Three cases combined with imperforate hymen and haematocolpos.

Diffuse vaginal adenosis is a rare disease presenting severe symptoms and difficult to treat. It has not previously been described in the Scandinavian literature. Three typical cases are reported, two in children of 14 years and one in a women of 20 years, who were all treated for imperforate hymen and haematocolpos. None of the patients had been subjected to oestrogen treatment in utero. The colposcopic findings are very characteristic and are described in relation to the histological examination. The pathogenesis, treatment and risk of malignant transformation are discussed.