Executive summary of the consensus document for recommendations on the treatment of venous thromboembolism in pregnancy: consensus document from the Spanish Society of Internal Medicine, the Spanish Society of Medical Radiology, the Spanish Society of Vascular Interventional Radiology and the Spanish Society of Gynecology and Obstetrics 2026.

INTRODUCTION: Low-molecular-weight heparin is the anticoagulant treatment of choice for managing venous thromboembolism (VTE) during pregnancy and lactation. Vitamin K antagonists are contraindicated between weeks 6-12 of gestation due to their association with a specific embryopathy, and during the third trimester due to the risk of bleeding. Direct oral anticoagulants are contraindicated during pregnancy and breastfeeding because of the risk of prenatal malformations. Reperfusion techniques, such as systemic thrombolysis or mechanical thrombectomy, are reserved for cases of pulmonary embolism with hemodynamic instability.

METHODS AND RESULTS: This consensus document, developed by the Spanish Societies of Internal Medicine, Medical Radiology, Vascular and Interventional Radiology, and Gynecology and Obstetrics, provides a comprehensive review of the most recent evidence on the treatment of VTE in pregnant patients and updates current recommendations.