Internal medicine (Tokyo, Japan) · 2019
Bromocriptine as a Potential Glucose-lowering Agent for the Treatment of Prolactinoma with Type 2 Diabetes.
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Oshige Tamami, Nakamura Yui, Sasaki Yuko, Kawano Seiko, Ohki Tsuyoshi, Tsuruta Munehisa, Tokubuchi Ichiro, Nakayama Hitomi, Yamada Kentaro, Ashida Kenji, Tajiri Yuji, Nomura Masatoshi
Аннотация
A 22-year-old Japanese woman consulted an endocrinologist due to persistent galactorrhea for the past 10 months. She had hyperprolacinemia and had previously been diagnosed with type 2 diabetes mellitus based on her glycohemoglobin level of 11.6%. After two months, she was admitted to our hospital and finally diagnosed with prolactinoma. For the treatment of prolactinoma, bromocriptine 2.5 mg/day was started. After seven days, her post-prandial blood glucose levels, homeostasis model assessment of insulin resistance and plasma C-peptide levels were significantly improved. These results indicate that traditional bromocriptine can be an effective therapeutic alternative in patients with prolactinoma complicated with type 2 diabetes.