Медицинская библиотека · Cell death and differentiation · 2023
Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Vitale Ilio, Pietrocola Federico, Guilbaud Emma, Aaronson Stuart A, Abrams John M, Adam Dieter, Agostini Massimiliano, Agostinis Patrizia, Alnemri Emad S, Altucci Lucia, Amelio Ivano, Andrews David W, Aqeilan Rami I, Arama Eli, Baehrecke Eric H, Balachandran Siddharth, Bano Daniele, Barlev Nickolai A, Bartek Jiri, Bazan Nicolas G, Becker Christoph, Bernassola Francesca, Bertrand Mathieu J M, Bianchi Marco E, Blagosklonny Mikhail V, Blander J Magarian, Blandino Giovanni, Blomgren Klas, Borner Christoph, Bortner Carl D, Bove Pierluigi, Boya Patricia, Brenner Catherine, Broz Petr, Brunner Thomas, Damgaard Rune Busk, Calin George A, Campanella Michelangelo, Candi Eleonora, Carbone Michele, Carmona-Gutierrez Didac, Cecconi Francesco, Chan Francis K-M, Chen Guo-Qiang, Chen Quan, Chen Youhai H, Cheng Emily H, Chipuk Jerry E, Cidlowski John A, Ciechanover Aaron, Ciliberto Gennaro, Conrad Marcus, Cubillos-Ruiz Juan R, Czabotar Peter E, D'Angiolella Vincenzo, Daugaard Mads, Dawson Ted M, Dawson Valina L, De Maria Ruggero, De Strooper Bart, Debatin Klaus-Michael, Deberardinis Ralph J, Degterev Alexei, Del Sal Giannino, Deshmukh Mohanish, Di Virgilio Francesco, Diederich Marc, Dixon Scott J, Dynlacht Brian D, El-Deiry Wafik S, Elrod John W, Engeland Kurt, Fimia Gian Maria, Galassi Claudia, Ganini Carlo, Garcia-Saez Ana J, Garg Abhishek D, Garrido Carmen, Gavathiotis Evripidis, Gerlic Motti, Ghosh Sourav, Green Douglas R, Greene Lloyd A, Gronemeyer Hinrich, Häcker Georg, Hajnóczky György, Hardwick J Marie, Haupt Ygal, He Sudan, Heery David M, Hengartner Michael O, Hetz Claudio, Hildeman David A, Ichijo Hidenori, Inoue Satoshi, Jäättelä Marja, Janic Ana, Joseph Bertrand, Jost Philipp J, Kanneganti Thirumala-Devi, Karin Michael, Kashkar Hamid, Kaufmann Thomas, Kelly Gemma L, Kepp Oliver, Kimchi Adi, Kitsis Richard N, Klionsky Daniel J, Kluck Ruth, Krysko Dmitri V, Kulms Dagmar, Kumar Sharad, Lavandero Sergio, Lavrik Inna N, Lemasters John J, Liccardi Gianmaria, Linkermann Andreas, Lipton Stuart A, Lockshin Richard A, López-Otín Carlos, Luedde Tom, MacFarlane Marion, Madeo Frank, Malorni Walter, Manic Gwenola, Mantovani Roberto, Marchi Saverio, Marine Jean-Christophe, Martin Seamus J, Martinou Jean-Claude, Mastroberardino Pier G, Medema Jan Paul, Mehlen Patrick, Meier Pascal, Melino Gerry, Melino Sonia, Miao Edward A, Moll Ute M, Muñoz-Pinedo Cristina, Murphy Daniel J, Niklison-Chirou Maria Victoria, Novelli Flavia, Núñez Gabriel, Oberst Andrew, Ofengeim Dimitry, Opferman Joseph T, Oren Moshe, Pagano Michele, Panaretakis Theocharis, Pasparakis Manolis, Penninger Josef M, Pentimalli Francesca, Pereira David M, Pervaiz Shazib, Peter Marcus E, Pinton Paolo, Porta Giovanni, Prehn Jochen H M, Puthalakath Hamsa, Rabinovich Gabriel A, Rajalingam Krishnaraj, Ravichandran Kodi S, Rehm Markus, Ricci Jean-Ehrland, Rizzuto Rosario, Robinson Nirmal, Rodrigues Cecilia M P, Rotblat Barak, Rothlin Carla V, Rubinsztein David C, Rudel Thomas, Rufini Alessandro, Ryan Kevin M, Sarosiek Kristopher A, Sawa Akira, Sayan Emre, Schroder Kate, Scorrano Luca, Sesti Federico, Shao Feng, Shi Yufang, Sica Giuseppe S, Silke John, Simon Hans-Uwe, Sistigu Antonella, Stephanou Anastasis, Stockwell Brent R, Strapazzon Flavie, Strasser Andreas, Sun Liming, Sun Erwei, Sun Qiang, Szabadkai Gyorgy, Tait Stephen W G, Tang Daolin, Tavernarakis Nektarios, Troy Carol M, Turk Boris, Urbano Nicoletta, Vandenabeele Peter, Vanden Berghe Tom, Vander Heiden Matthew G, Vanderluit Jacqueline L, Verkhratsky Alexei, Villunger Andreas, von Karstedt Silvia, Voss Anne K, Vousden Karen H, Vucic Domagoj, Vuri Daniela, Wagner Erwin F, Walczak Henning, Wallach David, Wang Ruoning, Wang Ying, Weber Achim, Wood Will, Yamazaki Takahiro, Yang Huang-Tian, Zakeri Zahra, Zawacka-Pankau Joanna E, Zhang Lin, Zhang Haibing, Zhivotovsky Boris, Zhou Wenzhao, Piacentini Mauro, Kroemer Guido, Galluzzi Lorenzo
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Аннотация
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have elucidated the key contribution of this process not only to (post-)embryonic development and adult tissue homeostasis, but also to the etiology of multiple human disorders. Consistent with this notion, while defects in the molecular machinery for apoptotic cell death impair organismal development and promote oncogenesis, the unwarranted activation of apoptosis promotes cell loss and tissue damage in the context of various neurological, cardiovascular, renal, hepatic, infectious, neoplastic and inflammatory conditions. Here, the Nomenclature Committee on Cell Death (NCCD) gathered to critically summarize an abundant pre-clinical literature mechanistically linking the core apoptotic apparatus to organismal homeostasis in the context of disease.
Для цитирования: Vitale Ilio, Pietrocola Federico, Guilbaud Emma, Aaronson Stuart A, Abrams John M, Adam Dieter, Agostini Massimiliano, Agostinis Patrizia, Alnemri Emad S, Altucci Lucia, Amelio Ivano, Andrews David W, Aqeilan Rami I, Arama Eli, Baehrecke Eric H, Balachandran Siddharth, Bano Daniele, Barlev Nickolai A, Bartek Jiri, Bazan Nicolas G, Becker Christoph, Bernassola Francesca, Bertrand Mathieu J M, Bianchi Marco E, Blagosklonny Mikhail V, Blander J Magarian, Blandino Giovanni, Blomgren Klas, Borner Christoph, Bortner Carl D, Bove Pierluigi, Boya Patricia, Brenner Catherine, Broz Petr, Brunner Thomas, Damgaard Rune Busk, Calin George A, Campanella Michelangelo, Candi Eleonora, Carbone Michele, Carmona-Gutierrez Didac, Cecconi Francesco, Chan Francis K-M, Chen Guo-Qiang, Chen Quan, Chen Youhai H, Cheng Emily H, Chipuk Jerry E, Cidlowski John A, Ciechanover Aaron, Ciliberto Gennaro, Conrad Marcus, Cubillos-Ruiz Juan R, Czabotar Peter E, D'Angiolella Vincenzo, Daugaard Mads, Dawson Ted M, Dawson Valina L, De Maria Ruggero, De Strooper Bart, Debatin Klaus-Michael, Deberardinis Ralph J, Degterev Alexei, Del Sal Giannino, Deshmukh Mohanish, Di Virgilio Francesco, Diederich Marc, Dixon Scott J, Dynlacht Brian D, El-Deiry Wafik S, Elrod John W, Engeland Kurt, Fimia Gian Maria, Galassi Claudia, Ganini Carlo, Garcia-Saez Ana J, Garg Abhishek D, Garrido Carmen, Gavathiotis Evripidis, Gerlic Motti, Ghosh Sourav, Green Douglas R, Greene Lloyd A, Gronemeyer Hinrich, Häcker Georg, Hajnóczky György, Hardwick J Marie, Haupt Ygal, He Sudan, Heery David M, Hengartner Michael O, Hetz Claudio, Hildeman David A, Ichijo Hidenori, Inoue Satoshi, Jäättelä Marja, Janic Ana, Joseph Bertrand, Jost Philipp J, Kanneganti Thirumala-Devi, Karin Michael, Kashkar Hamid, Kaufmann Thomas, Kelly Gemma L, Kepp Oliver, Kimchi Adi, Kitsis Richard N, Klionsky Daniel J, Kluck Ruth, Krysko Dmitri V, Kulms Dagmar, Kumar Sharad, Lavandero Sergio, Lavrik Inna N, Lemasters John J, Liccardi Gianmaria, Linkermann Andreas, Lipton Stuart A, Lockshin Richard A, López-Otín Carlos, Luedde Tom, MacFarlane Marion, Madeo Frank, Malorni Walter, Manic Gwenola, Mantovani Roberto, Marchi Saverio, Marine Jean-Christophe, Martin Seamus J, Martinou Jean-Claude, Mastroberardino Pier G, Medema Jan Paul, Mehlen Patrick, Meier Pascal, Melino Gerry, Melino Sonia, Miao Edward A, Moll Ute M, Muñoz-Pinedo Cristina, Murphy Daniel J, Niklison-Chirou Maria Victoria, Novelli Flavia, Núñez Gabriel, Oberst Andrew, Ofengeim Dimitry, Opferman Joseph T, Oren Moshe, Pagano Michele, Panaretakis Theocharis, Pasparakis Manolis, Penninger Josef M, Pentimalli Francesca, Pereira David M, Pervaiz Shazib, Peter Marcus E, Pinton Paolo, Porta Giovanni, Prehn Jochen H M, Puthalakath Hamsa, Rabinovich Gabriel A, Rajalingam Krishnaraj, Ravichandran Kodi S, Rehm Markus, Ricci Jean-Ehrland, Rizzuto Rosario, Robinson Nirmal, Rodrigues Cecilia M P, Rotblat Barak, Rothlin Carla V, Rubinsztein David C, Rudel Thomas, Rufini Alessandro, Ryan Kevin M, Sarosiek Kristopher A, Sawa Akira, Sayan Emre, Schroder Kate, Scorrano Luca, Sesti Federico, Shao Feng, Shi Yufang, Sica Giuseppe S, Silke John, Simon Hans-Uwe, Sistigu Antonella, Stephanou Anastasis, Stockwell Brent R, Strapazzon Flavie, Strasser Andreas, Sun Liming, Sun Erwei, Sun Qiang, Szabadkai Gyorgy, Tait Stephen W G, Tang Daolin, Tavernarakis Nektarios, Troy Carol M, Turk Boris, Urbano Nicoletta, Vandenabeele Peter, Vanden Berghe Tom, Vander Heiden Matthew G, Vanderluit Jacqueline L, Verkhratsky Alexei, Villunger Andreas, von Karstedt Silvia, Voss Anne K, Vousden Karen H, Vucic Domagoj, Vuri Daniela, Wagner Erwin F, Walczak Henning, Wallach David, Wang Ruoning, Wang Ying, Weber Achim, Wood Will, Yamazaki Takahiro, Yang Huang-Tian, Zakeri Zahra, Zawacka-Pankau Joanna E, Zhang Lin, Zhang Haibing, Zhivotovsky Boris, Zhou Wenzhao, Piacentini Mauro, Kroemer Guido, Galluzzi Lorenzo. Apoptotic cell death in disease-Current understanding of the NCCD 2023.. Cell death and differentiation. 2023. DOI: 10.1038/s41418-023-01153-w.
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