Nature clinical practice. Rheumatology · 2005
A woman with rheumatoid arthritis whose condition did not improve during pregnancy.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Østensen Monika, Raio Luigi
Аннотация
BACKGROUND: A 25-year-old woman with a 3-year history of rheumatoid arthritis presented 6 months before her first planned pregnancy. At the time of presentation, she was being successfully treated with infliximab and methotrexate. During her pregnancy, the patient discontinued infliximab and methotrexate and her arthritis relapsed. She was treated with low-dose prednisone, sulfasalazine, nimesulide, and intra-articular corticosteroid injections. Oligohydramnios developed at gestational week 18.
INVESTIGATIONS: Laboratory testing, ultrasonography of the fetus and of the patient's affected joints.
DIAGNOSIS: Active arthritis during pregnancy and oligohydramnios suspected to be caused by nimesulide.
MANAGEMENT: Low-dose oral prednisone, sulfasalazine, repeated intra-articular corticosteroid injections. Infliximab and methotrexate were restarted immediately after delivery.
INVESTIGATIONS: Laboratory testing, ultrasonography of the fetus and of the patient's affected joints.
DIAGNOSIS: Active arthritis during pregnancy and oligohydramnios suspected to be caused by nimesulide.
MANAGEMENT: Low-dose oral prednisone, sulfasalazine, repeated intra-articular corticosteroid injections. Infliximab and methotrexate were restarted immediately after delivery.